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Saturday, December 31, 2011
Another Shady Land Deal in Africa, This One Assisted By the U.S. Ambassador to Tanzania
Trees ForTheFuture/CC BY 1.0
Tree-planting in Mayange Village near Kigoma, Tanzania, where thousands of people would be displaced?some of them refugees from Burundi with over 40 years of established lives, according to the Oakland Institute.
The Oakland Institute?the think tank that revealed the connection this summer between Ivy League universities and land grabs in Africa?is now voicing concern about the support the U.S. ambassador to Tanzania is lending to a land deal in that country that would displace more than 160,000 people.
Displacing Refugee Populations with Unsustainable Agriculture
According to the Oakland Institute [PDF], the stated goal of the project is to commercially develop a site?which encompasses lands that have served as refugee resettlement areas since 1972?for large-scale crop cultivation, beef, and poultry production, and biofuel production.
The institute adds, "Agrisol?s vision is to accomplish this through industrial-style agriculture employing biotechnology and other high-technology inputs to be supplied by AgriSol?s business partners, including Monsanto, Syngenta, and other powerful global industrial agribusiness conglomerates."
The key player locally is AgriSol Energy Tanzania, which is a partnership between Iowa-based Agrisol Energy, LLC and Tanzania-based Serengeti Advisers Limited. This month, the Oakland Institute released a brief highlighting eight myths about AgriSol.
Meanwhile Alfonso Lenhardt, the U.S. ambassador, recently defended AgriSol's activities in the Rukwa and Kigoma region using one of the very myths mentioned in that brief. According to the Daily News in Tanzania:
"Agrisol have not grabbed any land but were actually invited by the Prime Minister when he visited Iowa state two years ago and saw how American technology can produce sufficient food and energy from farms," Lenhardt argued as senior media stakeholders expressed concern over allegations of land grabbing by Agrisol in western Tanzanian regions.
Food Security?
Here's what the Oakland Institute has to say about food security and how AgriSol stands to benefit from the deal: "While claiming to benefit Tanzanians and contributing to the country?s food needs, AgriSol?s internal documents reveal its intent, which includes agrofuel production and export markets."
More specifically:
While pitching the project as in the best national interest of Tanzania, AgriSol?s Tanzanian cohorts fail to mention AgriSol?s demand for ?Strategic Investor Status? to receive incentives including a waiver of duties on diesel, agricultural and industrial equipment and supplies; production of agrofuels, and request of the government to commit and provide a timetable for the construction of a rail link for Mishamo.
AgriSol will generate significant profits through the project. While it intends to invest $100 million over a 10 year period, if corn is cultivated on only 200,000 of the 325,000 hectares, net profits for the company could be $272 million a year, an amount which nearly equals the total budget of Tanzania?s Ministry of Agriculture. If they receive Strategic Investor Status it would include an exemption from corporate tax, currently 30 percent of this amount.
? AgriSol?s feasibility studies call for it to negotiate with the government for input subsidies, which for now are targeted for the smallholder Tanzanian farmers. If accepted by the government, such a demand will divert scarce public resources from smallholders to agribusiness.
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Friday, December 30, 2011
Wynonna Judd engaged to Cactus Moser
Love never permeates the air more than it does during the holiday season. Need proof?
Here you go: E! News has confirmed that country star Wynonna Judd is engaged to her musician beau of nearly two years, Cactus (that's right) Moser.
So, how'd the engagement go down?
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Happy 75th birthday, Mary Tyler Moore
Judd's rep confirmed to E! News that Moser popped the question to his longtime girlfriend on Christmas Eve. Merry holiday, indeed!
But in an effort to keep some things private, specific details about the proposal and engagement ring are, for now, being kept under wraps.
No wedding date has been set (or at least announced) for the personal and professional couple (they're currently touring together as Wynonna and the Big Noise), though it will be the third trip down the aisle for the 47-year-old singer.
She divorced hubby No. 2, J.D. Roach, in 2007, after four years of marriage and amid some damning accusations. Her first marriage, to Nashville businessman Arch Kelly III, ended in 1998. She has two children from that marriage, 17-year-old Elijah and 15-year-old Grace.
Congrats, you two!
PHOTOS: Celeb Weddings We Can't Wait For
? 2011 E! Entertainment Television, Inc. All Rights Reserved.
Source: http://today.msnbc.msn.com/id/45816192/ns/today-entertainment/
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In Iowa, Obama toils while GOP roars, then departs
President Barack Obama holds hands with his daughters Malia, left, and Sasha, right, as they leave Sea Life Park, a marine wildlife park, with family friends, Tuesday, Dec. 27, 2011, in Waimanalo, Hawaii. (AP Photo/Carolyn Kaster)
President Barack Obama holds hands with his daughters Malia, left, and Sasha, right, as they leave Sea Life Park, a marine wildlife park, with family friends, Tuesday, Dec. 27, 2011, in Waimanalo, Hawaii. (AP Photo/Carolyn Kaster)
Republican presidential candidate, former Massachusetts Gov. Mitt Romney speaks during a campaign stop at Elly's Tea and Coffee in Muscatine, Iowa, Wednesday, Dec. 28, 2011. (AP Photo/Chris Carlson)
Republican presidential candidate, former House Speaker Newt Gingrich makes a stop at the National Farm Toy Museum in Dyersville, Iowa, on Tuesday, Dec. 27, 2011, in Dyersville, Iowa. Gingrich also made stops in Dubuque and Decorah Tuesday afternoon and evening. (AP Photo/The Gazette, Nikole Hanna)
DES MOINES, Iowa (AP) ? One presidential campaign claims an impressive effort in Iowa this year: eight offices opened, 350,000 phone calls to potential supporters and 1,280 events to recruit and train volunteers.
It's not Mitt Romney or Newt Gingrich or Ron Paul. It's Obama for America, the president's re-election campaign, which badly wants to win this battleground state in November, as it did in 2008.
"The Republicans are here today, gone tomorrow," said Obama volunteer Pat Walters, of Johnston, a suburb of Des Moines. "We've been doing this since 2009."
Next Tuesday's Republican caucus has dominated political conversations. Largely overlooked is that Obama is running unopposed in the Democratic caucus the same night.
It's a dramatically different scene from four years ago, when Obama set his course for the White House by beating John Edwards and Hillary Rodham Clinton after months of intense campaigning in Iowa.
Obama can coast as far as this year's nomination is concerned. But Iowa remains a general election swing state, and no one assumes his 9-point win here over John McCain in 2008 will give him a cushion next November.
Obama's campaign never entirely left Iowa or several other competitive states, where he hopes relentless organizing can overcome a weak economy and his mixed record of fulfilling campaign pledges in the face of strong GOP opposition in Congress. If thousands of volunteers flocked to Obama's 2008 campaign, this time he's having to work a bit harder to recruit and energize them.
"People say, 'The mood is different this time, it's not the same,'" said Peggy Whitworth, an Obama volunteer in Cedar Rapids. "Well of course it's not the same. But it's not about mood or feeling. It's about the future of the country."
Whitworth, 69, said she joins other Obama volunteers four hours every Tuesday night, and sometimes on other evenings as well, to telephone potential supporters. Many say they will vote for Obama again, she said, and some volunteer to help the campaign. But some are disappointed or angry that the president fell short on campaign promises such as ending the Bush-era tax cuts for the wealthy, and bringing a greater spirit of bipartisanship to Washington.
"Sometimes they simply want to have someone listen to them," Whitworth said. Most say they will stick with Obama after they've had a chance to vent their frustrations, she said.
Obama lacks some key advantages he enjoyed in 2008. They include a deeply unpopular GOP president who was largely blamed for a faltering economy, and a widespread excitement about Obama's precedent-breaking campaign built on "hope and change."
In exchange, of course, he has the power of the presidency and a well-oiled political organization that has been refining its practices for five years. Obama will raise many millions of dollars, although his eventual Republican opponent may do nearly as well.
Nowhere does Obama have a bigger base to build on than in Iowa, where he campaigned for months in 2007. Romney, Gingrich and other GOP contenders have not made comparable efforts, although they say the economy and other issues will make Obama's task much harder next year.
In activities that rarely compete with the hoopla of the GOP nominating contest, Obama's campaign has placed a handful of paid staffers in each of several key states. They try to leverage their clout by recruiting and training scores of volunteers. The volunteers, in turn, knock on doors, organize house parties and, above all, place phone calls to voters in hopes of identifying likely Obama supporters and tracking them through Election Day.
In a tortoise-versus-hare strategy, Obama supporters hope their steady chugging will build support precinct by precinct, town by town, while Republicans spend resources chasing the nomination for a few more weeks or months. The Republican candidates and their broadcast ads are flooding Iowa this week, but they will abruptly shift to New Hampshire on Jan. 4, the day after the caucuses.
Walters, a 60-year-old insurance executive, said he is a "neighborhood team leader" who helps organize house parties, phone banks and other activities. His chief recruiting tools, he said, involve reminding Iowans of Obama's accomplishments that include expanding medical benefits in the hard-won 2010 overhaul of the nation's health care system.
Walters said he hopes the week-by-week, month-by-month effort will build a strong ground operation to turn out Obama's voters next November. The Republican nominee will have to play catch up, he said.
Obama's ground game "is already in place," Walters said. "It's just a matter of growing it."
Iowa Democratic Chairwoman Chair Sue Dvorsky underscored the methodical nature of the efforts in a conference call with reporters Wednesday.
Since April, she said, "this has been a systematic grassroots effort. The same exact way we did it last time. It isn't very glamorous. It's not a very secret plan. It is voter to voter, one-to-one, then a street, then a precinct, then a county."
Dvorsky said Obama will beam "a live address to Iowa Democrats in every caucus site next Tuesday night.
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Thursday, December 29, 2011
PokerStars: @sl4shy I don't know, contact your local twitter account @poker_starsFR or support through the client to find out :) thank you.
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@sl4shy I don't know, contact your local twitter account @poker_starsFR or support through the client to find out :) thank you. 
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U.S. approves Monsanto drought-tolerant GM corn (Reuters)
WASHINGTON (Reuters) ? Monsanto's genetically engineered, drought resistant corn is deregulated, the U.S. Agriculture Department said Thursday, clearing the variety for sale.
USDA approved the variety after reviewing environmental and risk assessments, public comments and research data from Monsanto.
Corn is the most widely grown U.S. crop and farmers grew 91.9 million acres of the feed grain this year, the second-largest area since World War Two.
In its 2009 petition for approval of its GM variety, Monsanto said 40 percent of crop losses in North America are due to sub-optimal moisture.
In a statement, Monsanto said it planned farm trials in the western U.S. Plains in 2012 to demonstrate the variety for growers and to generate data that will help guide Monsanto's commercial decisions.
"Our drought system is designed to help farmers mitigate the risk of yield loss when experiencing drought stress, primarily in areas of annual drought stress," said Hobart Beeghly, U.S. product management leader.
The drought-tolerant trait was part of a collaboration with the German chemical company BASF.
The major U.S. area for adoption of drought-tolerant corn would be the Plains, which produce one-quarter of the U.S. crop, Monsanto estimated, as well as similar dryland regions of Africa, Europe and Latin America.
USDA announced the variety, known as MON 87460, "is no longer considered a regulated article under our regulations governing the introduction of certain genetically engineered organisms."
(Reporting By Charles Abbott)
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Wednesday, December 28, 2011
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Tuesday, December 27, 2011
jheil: RT @NYMag: "Better to be lucky than loved," or, how Mitt Romney returned to the front of the GOP pack: http://t.co/trPKNmBu #earlyandoft ...
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"Better to be lucky than loved," or, how Mitt Romney returned to the front of the GOP pack: nym.ag/sam5L2 #earlyandoften @jheil 
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5 die of food poisoning at Mexican rehab center (AP)
MEXICO CITY ? Medical officials say five recovering drug addicts died and dozens of others were sickened by soy sausage served for Christmas dinner at a rehabilitation center in western Mexico.
Authorities were investigating whether the poisoning at the center in the city of Guadalajara was accidental or intentional. Drug cartels have taken over rehabilitation centers in parts of Mexico, forcibly recruiting addicts as hit men and smugglers. The invasions have led to mass shootings at the centers that have left dozens dead.
Alhy Daniel Nunez is a spokesman for the Red Cross in the western state of Jalisco, where Guadalajara is located. He said Monday that 37 people remained hospitalized, three of them in serious condition.
(This version CORRECTS numbers in first paragraph).)
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Monday, December 26, 2011
FBI joins search for missing Indiana girl
This undated photo provided by the Allen County Sheriff's Department shows Aliahna Lemmon. Numerous police officers and others are searching in Fort Wayne, Ind., for Lemmon, 9, who was last seen the morning of Friday, Dec. 23, 2011. Allen County Sheriff's Department Cpl. Jeremy Tinkel says investigators have no indication that Lemmon was abducted or what might have happened to her. (AP Photo/Allen County Sheriff's Department)
This undated photo provided by the Allen County Sheriff's Department shows Aliahna Lemmon. Numerous police officers and others are searching in Fort Wayne, Ind., for Lemmon, 9, who was last seen the morning of Friday, Dec. 23, 2011. Allen County Sheriff's Department Cpl. Jeremy Tinkel says investigators have no indication that Lemmon was abducted or what might have happened to her. (AP Photo/Allen County Sheriff's Department)
Garry and Pam Hammer of the Orange Township Search and Rescue has their dog that is trained to smell body remains search Northway mobile home park near Diebold Road and North Clinton Street in Fort Wayne, Ind. on Monday, Dec. 26, 2011. The Hammers, part of State of Indiana District 3 SAR K9 team, are involved in the continued search for Aliahna Lemmon, who has been missing since Friday. (AP Photo/The Journal-Gazette, Cathie Rowand) NEWS-SENTINEL OUT
During an interview Sunday, Dec. 25, 2011 Amber Story, left, Tarah's mom, and Tarah Souders talk about Tarah's daughter Aliahna Lemmon, 9, who is missing since Friday in Fort Wayne, Ind. (AP Photo/The Journal Gazette, Cathie Rowand)
FORT WAYNE, Ind. (AP) ? FBI agents joined the search for a missing 9-year-old Indiana girl with physical and emotional problems on Monday, descending on the mobile home park where she lived that's a known haven for registered sex offenders.
About a half-dozen people in black windbreakers, several of whom identified themselves as FBI agents, were at the mobile home park in Fort Wayne where Aliahna Lemmon went missing from a family friend's home on Friday. Some with search dogs were seen at a nearby storage facility.
FBI agents also were outside a trailer identified by the girl's step-grandfather, David Story, as her mother Tarah Souder's home. A box truck was backed up to the mobile home Monday night, and a sheriff's official said a forensics team was sweeping the trailer looking for evidence such as hairs and fibers.
Across the street more than 100 people gathered at a candlelight vigil and prayed for the girl's safe return. Story cried briefly as he thanked the crowd for their support.
Monday's renewed search came a day after local police significantly rolled back a coordinated effort by several law enforcement agencies, said Fort Wayne police spokesman Cpl. Jeremy Tinkel. He said the same size search could not be sustained on Sunday because of the Christmas holiday.
Local police haven't said what they think happened to Aliahna.
"Children don't just walk away during Christmastime," said David Story, Aliahna.'s stepgrandfather.
Meanwhile, agents at the scene Monday wouldn't say why the FBI was involved. An agency spokesman didn't immediately return phone calls and e-mails seeking comment.
More than 100 emergency workers conducted an extensive search Saturday for Aliahna around the rundown mobile home park on Fort Wayne's north side where she was last seen. No active search was done Sunday for the girl.
According to a state website, 15 registered sex offenders live at the mobile home park that numbers about two dozen homes.
Elizabeth Watkins, 52, who has lived at the park for six months with her 4-year-old granddaughter, said it's well-known that several sex offenders live in the neighborhood.
"It's scary," she said. "I don't know how a parent could leave their child alone."
Aliahna's mother, Tarah Souders, 28, told The Journal Gazette her daughter has vision and hearing problems and suffers from attention deficit disorder and emotional problems. She also has a history of sleepwalking, family members said.
Aliahna and her sisters were staying at a family friend's nearby home because their mother had been sick with the flu and Aliahna's stepfather works at night and sleeps during the day, The Journal Gazette reported Monday.
Mike Plumadore, 39, told the newspaper Sunday that he left the three girls in his mobile home about 6 a.m. Friday and went to a gas station about a mile away to buy a cigar. Authorities have said the store's surveillance video shows him there about that time.
"I had deadbolted the door," he said. "When I got back, all the girls was here."
He said he smoked his cigar and went back to sleep, then woke up about 10 a.m. when Aliahna's mother called. After that call, he realized the door to the home was unlocked and that Aliahna was gone. He said Aliahna's sisters, both 6 years old, told him that Aliahna had left with her mom.
Plumadore said it wasn't until he talked with Aliahna's mom about 8:30 p.m. that they realized she was missing and police were notified.
Plumadore is not listed on the state's website that lists registered sex offenders. He has a criminal record in Florida and North Carolina that includes convictions for trespass and assault, along with traffic and alchol-related offenses.
Tarah Souders said miscommunication between the two of them caused the delay in determining that Aliahna had vanished.
"She's never wandered off," Souders said. "She's never done anything like this before."
But Aliahna does have a history of sleepwalking, even unlocking doors and going outside while sleeping, said her grandmother, Amber Story.
"I just hope that she's not suffering or in pain," Story said.
Souders said her daughter also has vision and hearing problems and suffers from attention deficit disorder and emotional problems.
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Is Indian investment in Ethiopian farms a 'land grab?' (VIDEO)
Investment by Indian-owned Karuturi Global has raised questions about whether Ethiopia is literally giving away the farm, or conversely, launching a 'green revolution to help Ethiopia feed itself.
When an Indian company invests hundreds of millions of dollars in Ethiopian commercial farming, is it boosting Ethiopia's food reserves and modernizing agricultural practices? Or is it grabbing land and displacing Ethiopia's poorest citizens?
Skip to next paragraphThe debate over Indian-owned Karuturi Global's investments in Ethiopia's Gambella region may sound extreme, but it is representative of the strong emotions one finds across the developing world about the subject of agricultural investment.
In Ethiopia ? where critics are aghast at the government for inviting foreign capitalists to grow cash crops for export while millions still rely on handouts ? the rancor is hindering much-needed constructive discussion on how to improve a sector of the economy that employs most of the population.
The worldwide trend is not in doubt. Globally, about 45 million hectares (111 million acres) of farmland were leased in 2009, compared with a previous average rate of 4 million hectares a year, the World Bank says. More than 70 percent of the deals were in Africa, most of them in Sudan, Mozambique, Liberia, Ethiopia, Nigeria and Madagascar.
The reasons are equally clear. It is estimated that global food production will have to increase 70 percent by 2050 to feed 9 billion mouths. One way to contribute to this is to cultivate under-utilized land ? something which Africa has a relatively large stock of.
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Sunday, December 25, 2011
SHOWstudio: Happy holidays to all our twitter followers from Nick Knight and the team at SHOWstudio
Happy holidays to all our twitter followers from Nick Knight and the team at SHOWstudio Source: http://twitter.com/SHOWstudio/statuses/150923580857790464
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UPDATE 1-Softbank to quit on Myspace in Japan-Nikkei
Dec 23 (Reuters) - Softbank Corp will quit its domestic social networking site business after just five years, liquidating a joint venture with Rupert Murdoch's News Corp for the Japanese-language version of Myspace, the Nikkei business daily reported.
The 50-50 joint venture with U.S. media group News Corp will shut down at the end of January and be liquidated, the Nikkei reported. The Japanese-language service will be taken over by U.S. firm Myspace LLC, the newspaper added.
News Corp acquired Myspace for $580 million in 2005, when it was among the world's most popular websites, and the company's success in beating out rival Viacom Inc in a bidding war was viewed as a major victory for Murdoch.
However, since then Facebook eclipsed Myspace in popularity and in June, News Corp sold the website to advertising company Specific Media LLC and singer Justin Timberlake at a fraction of what it had paid.
News Corp continues to own its stake in the Japanese unit, the Nikkei said.
Launched in Nov. 2006, Myspace's Japanese service tied up with record labels and sought to tout itself as a way for artists to reach fans. But it failed to offer attractive content, and had only signed up about 1.08 million users as of August, not even a 10th of Facebook's tally, the paper said.
Source: http://feeds.reuters.com/~r/reuters/mergersNews/~3/DQRDgYy6tFc/softbank-idUSL3E7NM4U420111222
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Saturday, December 24, 2011
Dunham?s Sports opens store in Burlington
RBR Staff Writer
Published 19 December 2011
Published 19 December 2011
Dunham?s Sports, a US-based sporting goods chain, has unveiled a new location in Burlington at Fox River Plaza in the former Pick ?n Save space.
The new 55,000ft? store, which is about 25% larger than Dunham's average, features clothing brands including Adidas and Columbia, Nike and Under Armour, reported journaltimes.com.
The Burlington has expanded hunting and fitness departments, in addition to a large 'value area' featuring footwear at 30-50% off manufacturers' suggested prices.
Near the front of the new store is a seasonal game shop with pool, pingpong, air hockey and shuffleboard tables. The basketball area had backboard stands priced from about $200 to $1,700.
The large fitness area in the shop included many types of exercise equipment, weight benches and power towers. The footwear section includes special shoes and cleats for sports including soccer, hiking and wrestling.
The hunting department includes rifles and shotguns, tree stands and a full archery area including crossbows. A corner of the Burlington shop is devoted to licensed team apparel and college hoodies.
The Michigan-based Dunham's Sports operates more than 150 stores in 14 Midwestern states.
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Attendance increases at Washington high school fall state championships
The Washington Interscholastic Activities Association saw attendance increase for the second straight year for the WIAA/Dairy Farmers of Washington/Les Schwab Tires fall state championships.
The WIAA, which oversees high school sports, ended the fall season with 71,152 fans attending the five different sports tournament events, an increase of 1,585 from the 2010 fall season, according to a WIAA media release. The largest attended sport was football (semifinals and finals) with 40,196 fans, an increase of 671 from the previous year.
The highest change was volleyball, which had an additional 1,310 spectators from 2010 with a total of 14,236. The mark set an association record for volleyball (accurate attendance records for individual sports have been kept since 1997). State cross country rounded out the sports that increased in attendance with another record-setting figure of 5,407. The cross country event has seen a steady increase since 2005.
In addition to the attendance figures, the WIAA launched the WIAA Network, a cross-platform endeavor that delivered television and web coverage of the state championships. The figures of the new online portal showed that 59,370 unique viewers watched webcasts of the 3A, 4A girls soccer semifinals and finals, girls swim and dive championships and the football state semifinals and Gridiron Classic, which excludes the Root Sports broadcast of the 3A and 4A football finals. Semifinals for football had the highest number of unique views with 31,672. The portal's home page saw unique views of over 90,000 with a total page view count of 144,123, between Nov.1 and Dec. 3.
Source: http://feedproxy.google.com/~r/kensports/~3/Ro5HClPJJqc/135963888.html
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Messi takes vacation after 'spectacular' year
Associated Press Sports
updated 1:46 p.m. ET Dec. 21, 2011
BUENOS AIRES (AP) -Lionel Messi arrived in Argentina on Wednesday for his winter-break vacation following another trophy-laden year at Barcelona.
"I finish the year in a spectacular way," Messi said as he arrived in Buenos Aires. "It was a very good year achieving important things."
Messi, who said he will spend Christmas with his family in Rosario, scored twice in his club's 4-0 win over Brazilian club Santos in the Club World Cup final on Sunday and was named player of the tournament.
Real Madrid coach Jose Mourinho belittled that achievement, saying Barcelona had won "two little games" to take the title, but Messi said he was pleased with the latest victory.
"It was an important game because of what it meant, who we were playing against, and because it was a club final," Messi said.
Barcelona also won the Champions League - with Messi scoring in the victory over Manchester United in the final - and defended its Spanish league title ahead of archrival Real Madrid during a stellar year.
Messi is also favorite to be named FIFA's world player of the year for 2011 from a shortlist that includes his teammate Xavi Hernandez and Cristiano Ronaldo.
The only success that eludes Messi is a trophy with Argentina, which was eliminated from the Copa America in the quarterfinals despite hosting the tournament this year.
"I like to win things with my club and with the national team," Messi said. "Unfortunately, that hasn't happened for me with the national team yet, but we'll keep working with lots of enthusiasm and belief."
Some Argentine fans have expressed frustration that Messi has been unable to repeat his invincible form for Barcelona on the international stage.
Messi insisted he always tries "to do my best, to try to play like I do every match with Barcelona. Sometimes it comes off, sometimes it doesn't, but I always have people's support."
? 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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AFP - Getty ImagesTerry to be charged
England captain will face a criminal charge over allegations that he racially abused an opponent in the Premier League.
Source: http://nbcsports.msnbc.com/id/45752947/ns/sports-soccer/
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Friday, December 23, 2011
Scientists reveal how bacteria build homes inside healthy cells
Tuesday, December 20, 2011
Bacteria are able to build camouflaged homes for themselves inside healthy cells - and cause disease - by manipulating a natural cellular process.
Purdue University biologists led a team that revealed how a pair of proteins from the bacteria Legionella pneumophila, which causes Legionnaires disease, alters a host protein in order to divert raw materials within the cell for use in building and disguising a large structure that houses the bacteria as it replicates.
Zhao-Qing Luo, the associate professor of biological sciences who headed the study, said the modification of the host protein creates a dam, blocking proteins that would be used as bricks in cellular construction from reaching their destination. The protein "bricks" are then diverted and incorporated into a bacterial structure called a vacuole that houses bacteria as it replicates within the cell. Because the vacuole contains materials natural to the cell, it goes unrecognized as a foreign structure.
"The bacterial proteins use the cellular membrane proteins to build their house, which is sort of like a balloon," Luo said. "It needs to stretch and grow bigger as more bacterial replication occurs. The membrane material helps the vacuole be more rubbery and stretchy, and it also camouflages the structure. The bacteria is stealing material from the cell to build their own house and then disguising it so it blends in with the neighborhood."
The method by which the bacteria achieve this theft is what was most surprising to Luo.
The bacterial proteins, named AnkX and Lem3, modify the host protein through a biochemical process called phosphorylcholination that is used by healthy cells to regulate immune response. Phosphorylcholination is known to happen in many organisms and involves adding a small chemical group, called the phosphorylcholine moiety, to a target molecule, he said.
The team discovered that AnkX adds the phosphorylcholine moiety to a host protein involved in moving proteins from the cell's endoplasmic reticulum to their cellular destinations. The modification effectively shuts down this process and creates a dam that blocks the proteins from reaching their destination.
The bacterial protein Lem3 is positioned outside the vacuole and reverses the modification of the host protein to ensure that the protein "bricks" are free to be used in creation of the bacterial structure.
This study was the first to identify proteins that directly add and remove the phosphorylcholine moiety, Luo said.
"We were surprised to find that the bacterial proteins use the phosphorylcholination process and to discover that this process is reversible," he said. "This is evidence of a new way signals are relayed within cells, and we are eager to investigate it."
The team also found that the phosphorylcholination reaction is carried out at a specific site on the protein called the Fic domain. Previous studies had shown this site induced a different reaction called AMPylation.
It is rare for a domain to catalyze more than one reaction, and it was thought this site's only responsibility was to transfer the chemical group necessary for AMPylation, Luo said.
"Revealing that this domain has dual roles is very important to identify or screen for compounds to inhibit its activity and fight disease," he said. "This domain has a much broader involvement in biochemical reactions than we thought and may be a promising target for effective treatments."
During infection bacteria deliver hundreds of proteins into healthy cells that alter cellular processes to turn the hostile environment into one hospitable to bacterial replication, but the specific roles of only about 20 proteins are known, Luo said.
"In order to pinpoint proteins that would be good targets for new antibiotics, we need to determine their roles and importance to the success of infection," he said. "We need to understand at the biochemical level exactly what these proteins do and how they take over natural cellular processes. Then we can work on finding ways to block these activities, stop the infection and save lives."
###
The article is published in Proceedings of National Academy of Sciences
Purdue University: http://www.purdue.edu/
Thanks to Purdue University for this article.
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Source: http://www.labspaces.net/116189/Scientists_reveal_how_bacteria_build_homes_inside_healthy_cells
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PFT: Pats gain in race to top in AFC
Getty ImagesBroncos quarterback Tim Tebow quietly has been winning over his doubters in recent weeks.? And one of the few remaining naysayers is no longer saying nay.
V.P. of football operations John Elway, a Hall of Fame and two-time Super Bowl-winning quarterback with the Broncos, has been cool to the notion of naming Tebow the team?s quarterback of the future.? Even after a one-week detour from Tebowmania, Elway has offered Tebow a nearly unequivocal endorsement.
?Tim Tebow?s not going anywhere,? Elway told Arnie Stapleton of the Associated Press.? ?I mean, he?s going to be a Bronco and we?re going to do everything we can and hopefully he?s that guy.?
Elway also seems to regret his one-word (i.e., no) assessment of whether, after three straight wins and a 4-1 record under Tebow, Elway was any closer to believing that the team had found its long-term answer at quarterback.
?I think that comment was probably a little bit too blunt,? Elway said. ?Because I think the big picture with Tim is we?ve got to see the whole body of work.? And so really what you want to see with him is the improvement that?s going to happen over time.
?Because, he?s done what we knew he could do and where we?ve seen his progress is what he does within the pocket.? What we?ve said, and I said it when I first got here, was we know Tim?s a great player and what we?ve got to do is make him a great quarterback, and what I?ve learned is you?ve got to be able to win from within the pocket. . . .
?We want it to happen because of the competitor he is and what type of person he is and how he represents not only himself but represents the Broncos and the city,? Elway added. ?People have been watching him, so he?s a draw. But that?s where some time in the offseason [helps] and it comes down to timing and throwing.
?Do I think he?ll get there? Yeah, I do.?
It sounds, then, as if the Broncos are willing to give Tebow a full offseason as the unquestioned starter, with the opportunity to continue to address the flaws in his game as a passer.? And then Elway will assess the situation once again in 2012, based on the extent to which Tebow does ? or doesn?t ? improve.
Source: http://profootballtalk.nbcsports.com/2011/12/20/it-was-a-nice-week-for-the-patriots/related/
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Thursday, December 22, 2011
King Mo Backs Off 'Cancer Patient' Comments, Wants to Fight Where ...
In September, "King" Mo Lawal said he viewed Strikeforce as something like "a dying cancer patient," saying he was just waiting for the promotion he's been fighting in since 2009 to die. But Lawal doesn't feel that way anymore.With Lawal set to fight Lorenz Larkin on the January 7 Strikeforce card -- the first card on a new agreement between Zuffa and Showtime to keep Strikeforce alive through 2012 -- Lawal now views Strikeforce as alive and well.
"I was wrong to say it was a cancer patient. The cancer went into remission and Strikeforce is back," Lawal said on Monday's edition of The MMA Hour.
That doesn't necessarily mean, however, that Lawal will be part of Strikeforce in the long term. Lawal has made no secret that he'd like to be involved in bigger fights (and bigger paydays) in the UFC. And although he said his request for a fight with Rampage Jackson in Japan never came close to fruition, he said he's hoping for big fights and big money next year, after his current contract expires following the fight with Larkin.
"I've got one more fight on my contract and then my contract ends in February," Lawal said. "King Mo just wants to go where he can get paid and get paid without the check bouncing."
Lawal said he has no problem remaining with Strikeforce, and he wasn't upset to learn that Zuffa will continue to operate the UFC and Strikeforce separately, rather than absorb Strikeforce fighters into the UFC.
"I just hope they can get us good fights and get us paid well," Lawal said. "I'm not disappointed."
The 12-0 Larkin, who has come up through the Strikeforce Challengers series, represents an interesting challenge for Lawal. If Larkin can pull the upset, it would certainly hurt Lawal's negotiating position as he looks to sign a new contract, but Lawal doesn't see that happening.
"Get this win, which I will," Lawal said. "And then I'll see what the options are and see what happens."
Source: http://www.mmafighting.com/2011/12/20/king-mo-backs-off-cancer-patient-comments-wants-to-fight-wher/
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Monday, December 19, 2011
Michael Green's judicial nomination still on hold (Rochester Democrat and Chronicle)
Sunday, December 18, 2011
Death of Florida A&M drum major ruled a homicide
ORLANDO, Fla. (AP) ? A Florida A&M University drum major was severely beaten in a hazing incident last month and died within an hour, the state medical examiner said Friday in declaring it a homicide.
Robert Champion, 26, had bruises to his chest, arms, shoulder and back and internal bleeding that caused him to go into shock, which killed him, the office said.
Champion's Nov. 19 death and the severe beating of another band member during a hazing ritual three weeks earlier have brought new scrutiny to a culture of hazing within the Tallahassee school's famed Marching 100.
State and local authorities are investigating Champion's death. Any death involving hazing is a third-degree felony in Florida, but so far no charges have been filed. Three male band members were arrested in a separate probe into the recent beating of a female member whose thigh bone was broken.
Witnesses told 911 that Champion was vomiting before he was found unresponsive aboard a band bus outside an Orlando hotel after the school's football team lost to rival Bethune-Cookman.
The report by Dr. Sara Irrgang described Champion as "previously healthy" showing "no evidence of natural disease" except for a slightly enlarged heart. Immediately after the hazing, Champion complained of thirst and fatigue, then loss of vision and signs of shock, the report said.
The toxicology report was negative for drugs and alcohol and there was no injury to the internal organs.
Champion's father, Robert Champion Sr., said he knew his son had been hazed.
"We just need to figure out what we need to do now to get the hazing under control," Champion told The Associated Press from his home in suburban Atlanta.
The family's attorney, Christopher Chestnut, said the autopsy confirmed the family's worst fears: "Justice needs to be swift and immediate."
"We're not calling for dismantling of the band," he said. "There needs to be high-level scrutiny. The students are adults, but they're young adults."
Champion's name was repeatedly invoked during FAMU's winter graduation ceremony Friday by Narayan Prasad, a faculty and board member. He called on graduates to be "Champion Rattlers" and to help ensure that hazing never happens again.
Larry Robinson, assistant secretary of commerce in the Obama administration, acknowledged Champion in his commencement speech. He said there were "dark clouds in our midst" but he predicted the university would overcome the scrutiny and survive.
"The world is watching. Let them see, let them hear the real FAMU. Let them know we have been here 124 years and we plan to be here another and yet another."
News of the autopsy came soon after Gov. Rick Scott met privately with FAMU President James Ammons to discuss whether he should step down.
Ammons was reprimanded by the school's Board of Trustees, but the governor says he thinks Ammons should be suspended until multiple investigations are complete.
FAMU's president does not report directly to the governor. But the governor is responsible for selecting some of those who serve on the FAMU board of trustees. The governor also appoints most of the people who sit on the board of governors that oversees the State University System.
A couple hundred FAMU students protested late Thursday night outside the Governor's Mansion to show their support for Ammons. Scott eventually came outside and talked to them, but he did not back off seeking a suspension.
Ammons said he and the governor had a "great discussion" and he was considering the request.
"We all have the best interests of Florida A&M University at heart, we are going to do what's best for university," Ammons said.
A new wrinkle comes from the Southern Association of Colleges and Schools Commission on Colleges, which has warned that Scott's push to suspend Ammons could affect the school's accreditation because of "undue influence" on the board from outside.
Friday evening, Ammons and Florida A&M board chairman Solomon L. Badger III issued a statement saying that the medical examiner's findings concerned them,
"This information is extremely upsetting for all of us, even though it confirmed what we suspected," the joint statement said. "We again convey our deepest condolences to the Champion family. We will continue to cooperate with all agencies looking into the matter and are committed to creating a safe environment for the entire FAMU community and ensuring that this never happens again at FAMU."
Separately, a group of black Tallahassee ministers formed a task force charged with battling hazing at all historically black colleges and universities. Student leaders at FAMU have launched an initiative to encourage every student on campus to sign an anti-hazing agreement; clubs and organizations that don't sign risk being sanctioned by student government.
Hazing cases in marching bands have cropped up over the years, particularly at historically black colleges, where a spot in the marching band is coveted and the bands are revered almost as much as the sports teams. In 2008, two first-year French horn players in Southern University's marching band had to be hospitalized after a beating. A year later, 20 members of Jackson State University's band were suspended after being accused of hazing.
In 2001, FAMU band member Marcus Parker suffered kidney damage because of a beating with a paddle. Three years earlier, Ivery Luckey, a clarinet player from Ocala, Fla., said he was paddled around 300 times, sending him to the hospital and leaving him physically and emotionally scarred.
___
Fineout reported from Tallahassee, Fla. Associated Press Writer Leonard Pallats in Atlanta contributed to this report.
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IDC: iPad maintains tablet dominance, HP's TouchPad fire sale burned brightly
While the Android tablets continue to roll in, Apple can still lay claim to the lion's share of the tablet market according to IDC's latest report. Its research suggests that the iPad holds onto 61.5 percent of the worldwide market share, down from 63.3 percent last quarter. Android devices in total also saw a slight contraction, down from 33.2 percent to 32.4 percent. This is partly explained by the HP TouchPad's final hurrah, which rocketed the ill-fated webOS tablet up to third place with a 5 percent of share of tablet sales and an estimated 903,354 devices sold. Samsung maintained its Honeycomb tablet crown, nabbing 5.6 percent of all tablet sales. The Korean manufacturer was closely tailed by Barnes and Noble's Nook Color with 4.5 percent and Asus, arriving at fifth place with a four percent share. Tablets in total sold less than the analysts had predicted, although E-readers outperformed estimates, with 6.5 million E-readers sold in the third quarter, up 165.9 percent from last year. IDC expects some disruptive new tablets will spice up the fourth quarter results and you can take a look at its findings and predictions at the full press release below.
Continue reading IDC: iPad maintains tablet dominance, HP's TouchPad fire sale burned brightly
IDC: iPad maintains tablet dominance, HP's TouchPad fire sale burned brightly originally appeared on Engadget on Fri, 16 Dec 2011 05:46:00 EDT. Please see our terms for use of feeds.
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Saturday, December 17, 2011
Video: Retail Beef Prices Hit Record $4.50/lb
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Source: http://video.msnbc.msn.com/cnbc/45702657/
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Friday, December 16, 2011
Republicans muscle tax cut bill through House (AP)
WASHINGTON ? Defiant Republicans pushed legislation through the House Tuesday night that would keep alive Social Security payroll tax cuts for some 160 million Americans at President Barack Obama's request ? but also would require construction of a Canada-to-Texas oil pipeline that has sparked a White House veto threat.
Passage, on a largely party-line vote of 234-193, sent the measure toward its certain demise in the Democratic-controlled Senate, triggering the final partisan showdown of a remarkably quarrelsome year of divided government.
The legislation "extends the payroll tax relief, extends and reforms unemployment insurance and protects Social Security ? without job-killing tax hikes," Republican House Speaker John Boehner declared after the measure had cleared.
Referring to the controversy over the Keystone XL pipeline, he added, "Our bill includes sensible, bipartisan measures to help the private sector create jobs."
On a long day of finger pointing, however, House Democrats accused Republicans of protecting "millionaires and billionaires, `' and Senate Majority Leader Harry Reid, D-Nev., derided the GOP-backed pipeline provision as "ideological candy" for the tea party-set.
After the House vote, the White House urged Congress on in finishing work on extending the tax cuts and jobless aid. Press Secretary Jay Carney issued a statement that didn't mention the pipeline but renewed Obama's insistence that the legislation be paid for, at least in part, by "asking the wealthiest Americans to pay their fair share" in higher tax levies.
Lawmakers "cannot go on vacation before agreeing to prevent a tax hike on 160 million Americans and extending unemployment insurance," he said.
Republicans mocked Obama's objections to their version of the bill.
"Mr. President, we can't wait," said House Majority Leader Eric Cantor of Virginia, employing a refrain the White House often uses to criticize Republicans for failing to take steps to improve an economy struggling to recover from the worst recession in decades.
Voting in favor of the legislation were 224 Republicans and 10 Democrats, while 179 Democrats and 14 Republicans opposed it.
At its core, the measure did include key parts of the jobs program that Obama asked Congress to approve in September.
The Social Security payroll tax cuts approved a year ago to help stimulate the economy would be extended through 2012, avoiding a loss of take-home income for wage-earners. An expiring program of unemployment benefits for the long-term jobless would remain in place, although at reduced levels that the administration said would cut off aid for 3.3 million.
A third major component would avert a threatened 27 percent cut in payments to doctors who treat Medicare patients, a provision Republicans added to appeal to conservatives but one that the White House and Democrats embrace, too.
While the tax and unemployment provisions were less generous than Obama sought, he and Republicans clashed principally over steps to cover the estimated $180 billion cost of the measure, and on the proposed 1,700-mile Keystone XL oil pipeline from Canada through environmentally sensitive terrain in Nebraska to the Texas Gulf Coast.
Obama recently delayed a decision on granting a permit for the pipeline until after the 2012 election.
The payroll tax legislation was one of three major bills that Congress was struggling to finish before adjourning for the year, and by far the most contentious.
A measure covering Pentagon spending was ready for passage, and, separately, negotiators said they were close to a deal on a $1 trillion measure to fund most government agencies through the end of the budget year.
That deal was in limbo, though, with Obama and congressional Democrats using it as leverage to keep House Republicans at the table negotiating a final compromise on the tax and unemployment measure.
It was the final showdown of a year that once brought the government to the brink of a shutdown and also pushed the Treasury to the cusp of a first-ever default.
Those confrontations produced last-minute compromises.
This time, leaders in both parties stressed a desire to renew the unemployment tax cuts and jobless benefits that are at the core of Obama's jobs program.
Obama and most Democrats favor an income surtax on million-dollar earners to pay for extending the Social Security tax cut, but Republicans oppose that, saying it is a violation of their pledge not to raise taxes.
Instead, the House bill called for a one-year pay freeze and higher pension costs for federal workers, higher Medicare costs for seniors over $80,000 in income as well as other items to cover the cost.
Obama's veto message focused on economic issues ? which unite Democrats ? accusing Republicans of putting the burden of paying for the legislation on working families "while giving a free pass to the wealthiest and to big corporations by protecting their loopholes and subsidies."
Republicans drew attention at every turn to the pipeline, which is backed by some lawmakers in the president's party as well as by the blue-collar unions representing plumbers, pipefitters, electricians, carpenters and construction workers.
Estimates of the jobs that would be produced by pipeline construction vary widely but are in the thousands in a time of high national unemployment. The State Department estimated the total at about 6,000; project manager TransCanada put it at 20,000 directly, and Rep. Dave Camp, R-Mich., said in debate on the House floor it was more than 100,000.
Democrats aimed their criticism at the bill's impact on those who would bear the cost.
Rep. Sander Levin of Michigan, the party's senior lawmaker on the Ways and Means Committee, displayed a placard that said "Seniors sacrifice: $31 billion. Federal workers sacrifice: $40 billion. Unemployed Americans sacrifice: $11 billion. Millionaires and billionaires sacrifice: $0."
The bill also "spends $300 million on a special interest provision that helps a handful of specialty hospitals while cutting billions from community hospitals," he said, referring to a part of the measure that will raise federal Medicare payments to doctor-owned hospitals.
Rep. Eliot Engel, a New York Democrat, said he had an open mind about the pipeline but also said it had no legitimate role in the payroll tax bill.
Republicans argued otherwise.
Rep. Fred Upton of Michigan, the chairman of the House Energy and Commerce Committee, said the pipeline's construction would allow Canada to send one million barrels of oil a day into the United States, lessening domestic reliance on imports.
He said Canadian development of a pipeline is a certainty, and lawmakers needed to decide whether they wanted it to end up in the United States or "someplace like China."
As drafted by Republicans, the measure also would block the Environmental Protection Agency from issuing planned rules to limit toxic emissions from industrial boilers. Republicans said the regulation would be a job killer, and 41 Democrats supported an earlier stand-alone measure to prevent the administration from acting.
Other provisions to cover the cost of the legislation would repeal billions from the health care bill that Obama won from Congress last year when both the House and Senate were under Democratic control and from boosting fees that Fannie Mae and Freddie Mac charge banks for backing their mortgages.
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